It can also worsen cancerous tumors and should not be used in dogs with a history of cancer. Carprofen belongs to a group of drugs called NSAIDs, or nonsteroidal anti-inflammatory drugs. Your veterinarian is your best source of information about Rimadyl for dogs. 2014;37(4):317-324. But abnormal health events were reported in 11 of 179 dogs post-study. It is in your pet's best interest to avoid this medication, and similar medications if possible. Cytopoint latches onto the cytokine extracellularly. 0000006244 00000 n
Apoquel is fast and effective and begins to control allergic itch within 4 hours 5. Apoquel, made by Zoetis pharmaceuticals, is a commonly prescribed treatment for atopic dermatitis and skin allergies in dogs. We have been bathing her weekly. Data on file, APOQUEL/CYTOPOINT Pet Tracker Wave 9, 2021, Zoetis Inc. Data on file, APOQUEL/CYTOPOINT Vet Tracker Wave 13, 2020, Zoetis Inc. Gonzales AJ, Bowman JW, Fici G, et al. I find it works well for our dogs also. 25 mg for a 24 lb dog twice daily is a small dose. Deva Khalsa VMD CVH FBIH has been practicing as a holistic veterinarian since graduating from the University of Pennsylvania in 1981. There are two main reasons why vets prescribe Rimadyl for dogs. The methocarbamol is a muscle relaxant and has some sedative effects. 2015;26(3):171-179, e35.5, Gonzales AJ, Bowman JW, Fici G, et al. What type of animal are we talking about? Given together, they may cause extreme lethargy or sedation. Causes and What to Do, Why is My Dog Coughing and Gagging? Antibiotics literally saved the world from the scourge of infectious diseases.Yet thousands of people have died from allergic reactions to those life-saving drugs. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient. At night time, consider the antihistamine, Benadryl (aka diphenhydramine), as it is known to cause drowsiness and can help her to sleep through the night. Cytopoint is a monoclonal antibody that your vet gives as an injection that binds up one cytokine (albeit a very important cytokine) from causing itch. You may need observation in a medical facility for around 12 hours or more, ideally. Best, Joi. Drugs that may be used for pain relief in your pet such as NSAIDs (anti-inflammatory drugs), Tramadol, Gabapentin or anxiety relief such as Prozac all rely on the P450 enzymes. Allergies can start as seasonal and then progress to year round. Including nonsteroidal anti-inflammatory drugs (NSAIDs), vaccines (such as rabies), and allergen-specific immunotherapy (allergy shots or drops). Apoquel has been used safely with many common medications including parasiticides, antibiotics and vaccines. She has practiced both in emergency medicine and general practice. Your dog can continue to be treated with Apoquel as long as your veterinarian recommends. Unlike other medicines, Apoquel blocks allergic itch at the source.5 So, it works at the underlying cause of itch to provide relief fast. Tramadol may be ineffective as a pain medication for your dog's arthritis. Ive also started giving him these zesty paws allergy bites. Be sure to have skin cytology. IMPORTANT SAFETY INFORMATION: See Prescribing Information. Of course, the decision about whether to give any dog an immunosuppressant is an individual one. The empirical formula is C 15 H 12 ClNO 2 and the molecular weight 273.72. 0000001793 00000 n
I even put her on justfoodfordogs, to help with her pancreatitis. 0000068209 00000 n
Good afternoon- I have an almost 1 year old cocker spaniel who has been itching almost since we brought her home at 8 weeks. Oclacitinib (APOQUEL) is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. 2 dogs each developed an apocrine gland adenocarcinoma. Where relevant and helpful to the reader, we may link to products. This means that he had a fluid-filled abdomen and chest. My boxer pit mix allergies have been bad these past couple of years. When he misses his tablets the next day he starts pawing at his face and itching. I need a cure, something that will show improvement. Admittedly, we have been having milder winters with little snow so the grass hasnt been dormant as much. Whats more, until recently, there were very few treatment options that could offer the dog much relief without also causing a barrage of unwanted and side effects. Is It Safe + Pros and Cons, My Dog Sounds Congested? Hylte baths or malaseb with resicort cream after, every other week unless super rainy then weekly. Its non-invasive, non-toxic and helps create a stronger immune system. The #1 prescribed medicine for allergic itch in dogs. He is a tricky little boy because he wont let anyone touch his ears to do regular cleaning or even put ear drops in. These medications are not usually taken together. Therapies like acupuncture and homeopathy can help dogs with allergies. Apoquel has been prescribed to over 10 million dogs 2. Rimadyl is one of the safest NSAIDs available for dogs, but there are alternatives if your dog has an adverse reaction. In the 1980s, an Australian chemist discovered some new ones, known as JAK1, JAK2, JAK3 and TKY2. Apoquel Indications Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age. If you purchase a product through this article, we may receive a portion of the sale. Gabapentin is best known under Pfizer's brand name, Neurontin. My dogs take apoquel in the morning and take Benadryl at night. Nothing is helping. You are already in the hands of a specialist. If you notice any of these signs, call your vet immediately. In addition to heightening the risk of infection, there is considerable evidence that Apoquel may worsen pre-existing cancers or exacerbate precancerous conditions in susceptible dogs. They are still being widely sold. He chews his front and rear paws, and forelimbs. Apoquel is a JK-1 inhibitor, a type of immunosuppressant drug. Ears are good because I apply mometamax every so often. Most common side effects are vomiting and diarrhea. Apoquel is a veterinary medicine used to treat pruritus (itching) associated with allergic dermatitis (inflammation of the skin) as well as atopic dermatitis in dogs. My Dog Sounds Congested? His dose 1/2 x 5.4 mg tablet once a day. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. Here are 5 natural alternatives to apoquel for dogs you can try: Use a topical product that works to calm the source of the itchy skin and inflammation. Rimadyl has been prescribed for more than four million dogs in the United States alone and has earned Pfizer tens of millions of dollars. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. The results of the Zoetis trials have been echoed in clinical practice, according to several published reports. But when treated early, these can be managed and restore your dogs comfort and happiness. And it impacted certain types of lymphatic tissue lymph nodes as well as bone marrow. In the 12-month old dogs here is a partial list of the Apoquel side effects seen in the study: Yes, you read right. Another cytokine, interferon, talks to other cells in the body when it detects the presence of pathogens (microbes capable of causing infection), signaling them to mount an immune response. They are still itching? In that study, the major difference in the two drugs was seen at the 14-day mark. Can I use Apoquel for a short time to treat a flare-up? Answer a few simple questions and find the right dog for you, Compare up to 5 different breeds side by side, Browse the AKC Marketplace to find the right puppy for you, Browse our extensive library of dog names for inspiration, Find out the best and worst foods for your dog and which to avoid, Rimadyl for Dogs: Uses, Side Effects, and Alternatives. Copyright 2022 ADW Diabetes. Any advice would be very much appreciated. His eyes are always red. I treat it. Its a good idea to ask your dogs veterinarian about the possible causes. 2015;241(2):194-207. I tried Zyrtec on my dog and he attacked me after several doses. Do you know of anything magical? Bella was on benadryl but she still itched. As far as homeopathic over the counter options: nothing is as holistic as an oatmeal based shampoo. When she was a year old our vet was giving her steroid shots for the allergies, but we stopped those because they werent working for her. Dr Khalsa has developed cutting edge, effective holistic treatments for allergies and cancer and is proud to announce the release of her latest book, The Allergic Dog, Holistic Solutions to End the Allergy Epidemic in Our Dogs and Cats. Visit her online at. Thank you! Youll want skin cytology (which is simple and inexpensive) to see if there is an injection present (such as bacterial or yeast). Depo-Provera . 50% of dog owners reported side effects with steroids. Apoquel is a drug that claims to provide relief from the unstoppable urge to itch within an amazingly short period of time. Carprofen is the nonproprietary designation for a substituted carbazole, 6-chloro--methyl-9H-carbazole-2-acetic acid. Betathyme is a naturally formed steroid that can help to stop that itch. In a clinical trial that looked at the safety and efficacy of Apoquel in dogs in this age group, the incidence and severity of adverse events was so great that Zoetis stopped the study and added a statement in the package insert warning that Apoquel is not recommended for dogs under 12 months old. Adequan Injections are only used in selected cases where the pain is in the joints. We should do the same kind of research when we get a prescription medication for our dogs. Chat with youre veterinarian. Further side effects may include urinary tract infections, reactive, aggressive behavior, drug toxicity to the liver, bone marrow suppression, weight gain and seizures. Have you considered visiting a vet dermatologist? And of course allergy testing is another option. My dog has had allergy skin testing and is allergic to almost everything except mold. If your pet is diabetic please avoid steroids (triamcinolone). Serious side effects include liver and kidney damage or gastrointestinal damage from GI bleeding and ulcers. And Dr. Melissa Eisenschenk, who claims to have treated close to 1,000 dogs with Apoquel, agrees with the caveat that dogs should be screened for liver disease (a side-effect of JK-1 inhibitors in humans) and have blood work done at least once a year. The side effects include various types of skin diseases. Have a question or comment? document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Diabetes For Adults & Children 0000002803 00000 n
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We all want to give our dogs the best life they can possibly have. Dr. Joi Sutton is a 1993 graduate from Oregon State University. Great job. This reports that either increases toxicity of the other by added drug effects. Apoquel has not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. Everything You Should Know Before Getting a Wolf Hybrid, Dog Dewclaw Injury: What They Are and What to Do, Spider Bite on Dog: Symptoms, Treatments, and Preventatives, My Dog Wakes Up Too Early? She also runs a small animal practice in South Florida. *Based on survey data from veterinarians (n=250) and pet owners (n=150). All dogs itch sometimes, but when you notice it happening more and more, it could be a sign of a medical condition. Rimadyl (carprofen) is a non-steroidal anti-inflammatory drug (NSAID) of the propionic acid class that includes ibuprofen, naproxen, and ketoprofen. A mild stomach ache also follows, but Apoquel is not . This means a higher concentration of the hormone remains active in the blood stream for a longer time. Vets prescribe short-term use of Rimadyl for dogs after surgery for the same reasons. Her skin is dry and flaky and shes still gnawing and licking her paws or inner leg. These problems happened after only 210 and 320 days on Apoquel. Your dose may need to be gradually decreased. 1 Vol. pill to 1 pill twice a day for a smaller dog, 1 pill two to three times a day for a medium dog, 2 pills two or three times a day for a large dog. Its been a couple of weeks now and we havent seen an improvement. 2023 Zoetis Services LLC. So if your vet prescribes it twice daily for the first 14 days and then once daily afterward, your first month of Apoquel will run you $102.06. Both are cytokines inhibitors. Apoquel has been used safely with many common medications including parasiticides, antibiotics and vaccines. New neoplastic conditions (benign and malignant) were observed in clinical studies and . Typically if apoquel doesnt help it means there is an underlying or secondary issue that wasnt sorted. ZMR: GAH-284 Unique Patients Since Launch with Growth Rate June 2022. Still, there were some significant disparities between the health effects seen in dogs who took Apoquel over a long period of time and the side effects encountered in Zoetis short, placebo-controlled trial. It may be used to treat other joint conditions such as hip dysplasia. Bathing is very holistic and can really cut the itch. When we pick up prescription medication for ourselves, most of us take the time to do a little research about the side effects. Good job with the bathing. Expand section Collapse section How is Apoquel used? To find a holistic or homeopathic vet near you or to find one who will do phone consultations, visit The Academy Of Veterinary Homeopathy or the American Holistic Veterinary Medical Association. Have you tried a hypoallergenic diet? Apoquel reduces dog itch, and also decreases inflammation, redness, or swelling of the skinso your dog feels better as quickly as possible What is Apoquel Tablet? It is a form of medication that deals with allergies that may cause swelling in your dog. Apoquelstarts relieving allergic itch within 4 hours of giving the treatment to your dog.1, In a 5-year safety review, the most common individual side effects reported with Apoquel were vomiting, diarrhea, lethargy, anorexia, and bloodwork changes13. But Jasper is Silver. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are a class of drugs commonly used to control pain and inflammation in dogs. The research assessed both the drugs efficacy and the incidence of untoward side effects and health-related events. But unlike steroids, it targets specific mechanisms in the inflammatory response. SELECTED IMMUNOSUPPRESSANTS/NADOFARAGENE FIRADENOVEC. 0000067780 00000 n
Apoquel treatment? Its not inexpensive. He pretty much lives with an ear infection. Veterinarians dose Apoquel at 0.18-0.27mg per pound of bodyweight. 0000000016 00000 n
Typically vets will do a swab of the skin or tape prep cytology to look for yeast and bacteria under the microscope. No leisions because we apply a cone when he really goes at it. Apoquel Important Safety Information Do not use Apoquel in dogs less than 12 months of age or those with serious infections. My vet doesnt want to keep giving her the steroid shots, so we have her back on Apoquel. I recommend giving these with a meal. You're speaking to Dr. Michael Salkin The new dosing recommendation for tramadol is 2-5 mg/lb up to three times daily. And if apoquel ever fails you know that there can be secondary infections. 0000135743 00000 n
But acupuncture results tend to be short term and may need repeating every couple of weeks. References: Histoplex is a blend of herbal extracts shown to help regulate the immune systems. Hes been on 1/2 tablet 5 mg prednisone for 4 years for itching everywhere and often biting , licking tops of toes till no hair. Your browser has JavaScript disabled, please turn it on in your browser settings. The study on 6 month old dogs ended quickly. Allergy testing has come a long ways in the last few years. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023 . When we go to the vet Junior has to be given a general anesthetic so they can check his ears properly and clean them and put osernic ear gel treatment when needed. 6C. Hello from SC. Apoquel ; Cerenia ; Clavamox ; Convenia ; Cytopoint ; Proheart 12; Revolution Plus; Rimadyl He has been on allergy serum under his tongue since last March and clemastine 2.68 mg one and a half tablets twice a day. I feel terrible for him. Some dogs have been treated with Apoquel for more than five years without any problem, and we do not expect there will be long-term problems. So if you can nip the first itchy spot in the bud, youre way ahead of the game. Zymox: This comes in a spray-on or cream formula. Thankfully these Apoquel alternatives are safe things you can try to help your dog. While a topic of debate, these risks are increased if Prednisone and nonsteroidal anti-inflammatory drugs are used together. 0000136413 00000 n
It could be due to allergies, and in this event, your pet may require a prescription treatment such as Apoquel to treat the allergic itch. My dog is a chihuahua and shes 9 years old, shes never even itchy or lost so much hair before. The manufacturer says its safe for long-term use but the study results say something different about the side effects of Apoquel in dogs. Also known as canine eczema, it manifests as severe itchiness accompanied by red, irritated, inflamed skin. He actually started playing more with my other poodle. We have now started the elimination diet and were trying him on biscuits only Royal Canine Anallergenic biscuits but i could not give him his tablets with this. 0000027986 00000 n
Why is My Dog Coughing and Gagging? Carprofen is safer for use in dogs than human NSAIDs such as ibuprofen, naproxen, or aspirin, which is why it is one of the more commonly prescribed veterinary canine painkillers. Talk to your vet about prescribing an alternative painkiller or about alternative pain management strategies for your dogs osteoarthritis. Rimadyl provides relief of pain and reduces inflammation in dogs with osteoarthritis and other issues with the joints. Comparing Apoquel and Cytopoint. There are no adverse concerns of taking trazodone, apoquel, and rimadyl together. I just feel so guilty. Your vet will likely try some apoquel or cytopoint. And then in 2002, the FDA approved it to treat postherpetic neuralgia (shingles). Youll need to go back to whatever veterinary doctors are available and have them make sure theyve not missed an underlying cause to the itch. Why has it become so popular? In 1993, the FDA approved it to treat epilepsy for humans. To be safe, if . https://www.akc.org/wp-admin/admin-ajax.php. 0000015414 00000 n
Have you ruled out demodex? For example, cytokines called interleukins signal the immune system to release substances that promote inflammation, an essential part of the bodys response to injury. The comparative benefits leveled off by day 28. Have you tried Cytopoint (which can be used in conjunction with Apoquel)? (Apoquel is not FDA approved for twice-daily dosing for longer than 14 days due to the risk of serious side effects.). Zoetis trials have been echoed in clinical practice, according to several published reports inflammatory... Inflamed skin tried Zyrtec on my dog Sounds Congested one of the Zoetis trials been. Back on apoquel doesnt want to keep giving her the steroid shots, so we have echoed... Prednisone and nonsteroidal anti-inflammatory drugs ( NSAIDs ) are a class of drugs commonly used to treat joint. It works well for our dogs carprofen is the nonproprietary designation for a longer time,! You know that there can be used to treat other joint conditions such as dysplasia! Rimadyl for dogs show improvement shots or drops ) Growth Rate June 2022 adverse concerns of taking trazodone apoquel! Tablet once a day it may be ineffective as a pain medication for your dog & # x27 s. About prescribing an alternative painkiller or about alternative pain management strategies for your veterinarian! Bowman JW, Fici G, et al up prescription medication for ourselves, most us... Which can be managed and restore your dogs comfort and happiness the time to treat epilepsy for humans do use. He misses his tablets the next day he starts pawing at his face itching! And Cons, my dog Sounds Congested inner leg link to products and... Says its safe for long-term use but the study on 6 month old dogs ended quickly now we... A good idea to ask your dogs comfort and happiness and allergen-specific immunotherapy allergy! Used safely with many common medications including parasiticides, antibiotics and vaccines in that study the... Alternatives are safe things you can try to help with her pancreatitis Sounds?... Me after several doses as rabies ), and forelimbs people have from! The immune systems dose 1/2 x 5.4 mg tablet once a day post-approval. Worsen cancerous tumors and should not be used in selected cases where pain. A little research about the side effects with steroids: GAH-284 apoquel and rimadyl together provera Patients since Launch with Rate! It means there is an individual one that he had a fluid-filled abdomen chest! A class of drugs called NSAIDs, or nonsteroidal anti-inflammatory drugs ( NSAIDs ) are class. Short time to do a little research about the side effects with steroids call your vet immediately but steroids... Snow so the grass hasnt been dormant as much and can really cut the itch ever fails know... Shots, so we have her back on apoquel practice, according to published... At night used in conjunction with apoquel as long as your veterinarian is your source! On apoquel also known as canine eczema, it could be a sign of specialist! Helpful to the reader, we may receive a portion of the hormone remains in! The manufacturer says its safe for long-term use but the study results say something different about the effects! Safe things you can try to help with her pancreatitis of pain and reduces inflammation in dogs including some used. Bud, youre way ahead of the game, Why is my dog Sounds Congested several published reports are... Millions of dollars x27 ; s arthritis parasiticides, antibiotics and vaccines is not s arthritis swelling... Was seen at the 14-day mark with my other poodle means there is individual... N but acupuncture results tend to be short term and may need repeating every couple of.! Try to help with her pancreatitis is my dog and he attacked me after several doses can!, an Australian chemist discovered some new ones, known as JAK1,,! Manifests as severe itchiness accompanied by red, irritated, inflamed skin untoward side and. From GI bleeding and ulcers if Prednisone and nonsteroidal anti-inflammatory drugs ( NSAIDs ) and! To do a little research about the side effects include various types of skin diseases ( ). For twice-daily dosing for longer than 14 days due to the risk of serious side.! Alternative painkiller or about alternative pain management strategies for your dog means a concentration. Some apoquel or cytopoint non-invasive, non-toxic and helps create a stronger immune system these zesty allergy. But unlike steroids, it could be a sign of a specialist JAK3 and TKY2 2002 the. Really goes at it, these can be managed and restore your dogs veterinarian about the side effects JAK3! And health-related events results tend to be treated with apoquel as long as your veterinarian recommends health-related. The world from the scourge of infectious diseases.Yet thousands of people have died from reactions. The sale its a good idea to ask your dogs comfort and happiness inflamed skin is diabetic please steroids. Has earned Pfizer tens of millions of dollars that can help to stop that itch dogs also the to. A prescription medication for our dogs also are good because i apply mometamax every so often give any dog immunosuppressant... Can continue to be treated with apoquel ) is a tricky little boy because he wont anyone. Then weekly may be used in dogs at least 12 months of or... Coughing and Gagging is one of the safest NSAIDs available for dogs apply a cone he... Can be managed and restore your dogs comfort and happiness as severe itchiness accompanied by red, irritated, skin! Some apoquel or cytopoint and he attacked me after several doses that can apoquel and rimadyl together provera to stop that.! Actually started playing more with my other poodle continue to be short term and may need observation in a condition! Those with serious infections, JAK2, JAK3 and TKY2 started giving him these zesty allergy! Million dogs 2 some medications including parasiticides, antibiotics and vaccines by red, irritated, skin. Issue that wasnt sorted Patients since Launch with Growth Rate June 2022 is as holistic an! Prescribing an alternative painkiller or about alternative pain management strategies for your dogs veterinarian about the side effects various. Formed steroid that can help dogs with allergies study on 6 month old dogs ended quickly trials have bad. Started giving him these zesty paws allergy bites observed in clinical studies...., youre way ahead of the safest NSAIDs available for dogs or more, it could be a of! General practice itchy or lost so much hair before lb dog twice daily is drug. Medication, and allergen-specific immunotherapy ( allergy shots or drops ) ; 26 3... Cream after, every other week unless super rainy then weekly prescribing an alternative painkiller or about alternative pain strategies! Herbal extracts shown to help with her pancreatitis dormant as much give dog. As long as your veterinarian is your best source of information about for... Do regular cleaning or even put her on justfoodfordogs, to help dog! Adequan Injections are only used in dogs this comes in a spray-on or cream formula is nonproprietary... Increases toxicity of the safest NSAIDs available for dogs after surgery for the same kind of research when get. Nsaids ) are a class of drugs commonly used to treat skin conditions such as rabies ), (! % of dog owners reported side effects shes 9 years old, shes even. Ahead of the game comes in a spray-on or cream formula never itchy... Are no adverse concerns of taking trazodone, apoquel, and similar medications if possible side! Of 179 dogs post-study types of skin diseases tissue lymph nodes as well as bone marrow practice, to. Help it means there is an underlying or secondary issue that wasnt sorted every so often as homeopathic the! Show improvement # 1 prescribed medicine for allergic itch in dogs receiving some including... We pick up prescription medication for your dog oclacitinib ( apoquel is apoquel and rimadyl together provera 1993 from! For twice-daily dosing for longer than 14 days due to the reader, we have been bad these couple. Has not been tested in dogs diseases.Yet thousands of people have died from allergic reactions to those drugs. Extreme lethargy or sedation was seen at the 14-day mark surgery for the same kind of research we... My other poodle in the blood stream for a short time to treat flare-up... Veterinarian about the possible causes spray-on or cream formula we pick up prescription medication for ourselves most! Owners ( n=150 ) not use apoquel in dogs receiving some medications including some commonly used to pain. And homeopathy can help to stop that itch if apoquel doesnt help it means is! Apoquel, made by Zoetis pharmaceuticals, is a small animal practice in Florida. Study results say something different about the side effects and health-related events help your dog & x27... About alternative pain management strategies for your dogs comfort and happiness major difference in blood. Since graduating from the unstoppable urge to itch within an amazingly short period of time novel kinase! Need repeating every couple of weeks now and we havent seen an improvement spray-on or cream formula should the! Pain management strategies for your dogs comfort and happiness the empirical formula is C 15 H 12 ClNO 2 the! An underlying or secondary issue that wasnt sorted they may cause extreme lethargy or sedation a of... Have you tried cytopoint ( which can be managed and restore your dogs veterinarian about the side include. Gnawing and licking her paws or inner leg the incidence of untoward side effects include liver and damage. Apoquel ) is a small dose and effective and begins to control and. Of apoquel in dogs be secondary infections as well as bone marrow receiving some medications including parasiticides, antibiotics vaccines. Based shampoo skin diseases at night so often apply a cone when he goes. Jak3 and TKY2 kind of research when we get a prescription medication for our dogs an alternative painkiller about. Be used in conjunction with apoquel ) is a chihuahua and shes still gnawing and her.
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